Evaluating Conformal Reliability of Pathway-Level Transcriptomic Signatures Under Cross-Cohort Shift in Sepsis Mortality Prediction

arXiv:2607.17405 · q-bio.GN · Submitted 2026-07-19 · Read on arXiv

q-bio.GN

Submitted: 2026-07-19

Updated: 2026-10-18

Terminology

• Calibration — 2× in this paper · explained in 9 episodes
• AUROC — 1× in this paper · explained in 3 episodes
• Coherence — 1× in this paper · explained in 2 episodes
• Conformal Prediction — 1× in this paper · explained in 10 episodes
• External Validation — 1× in this paper · explained in 2 episodes
• Ontology — 1× in this paper · explained in 2 episodes
• Robustness — 1× in this paper · explained in 5 episodes
• Transferability — 1× in this paper · explained in 5 episodes
• XGBoost — 1× in this paper · explained in 2 episodes

Related papers

• WTKO-CNN: Deep Learning Reveals Sequence Motifs Distinguishing Wild-Type and Knockout ATAC-seq Peaks
• Robust Machine Learning for Regulatory Sequence Modeling under Biological and Technical Distribution Shifts
• Stable-Shift: Biologically Structured Prediction of Transcriptional Responses to Unseen Gene Perturbations