A digital-twin framework for forecasting treatment-day imaging with contour uncertainty in adaptive proton radiotherapy

arXiv:2609.24725 · physics.med-ph, cs.AI · Submitted 2026-09-21 · Read on arXiv

physics.med-ph, cs.AI

Submitted: 2026-09-21

Updated: 2026-09-21

License: http://arxiv.org/licenses/nonexclusive-distrib/1.0/

Terminology

• Digital Twin — 18× in this paper · explained in 5 episodes
• Adaptation — 17× in this paper · explained in 1 episode
• Alignment — 7× in this paper · explained in 1 episode
• Calibration — 6× in this paper · explained in 7 episodes
• Uncertainty Quantification — 6× in this paper · explained in 8 episodes
• Accuracy — 4× in this paper · explained in 1 episode
• Fidelity — 4× in this paper · explained in 2 episodes
• Robustness — 4× in this paper · explained in 5 episodes
• Aggregation — 3× in this paper · explained in 1 episode
• Anisotropy — 3× in this paper · explained in 3 episodes
• Epistemic Uncertainty — 2× in this paper · explained in 10 episodes
• Monte Carlo dropout — 2× in this paper · explained in 2 episodes
• Quantization — 2× in this paper · explained in 12 episodes
• AUC — 1× in this paper · explained in 2 episodes
• Accountability — 1× in this paper · explained in 2 episodes
• Aleatoric Uncertainty — 1× in this paper · explained in 5 episodes
• Bayesian Inference — 1× in this paper · explained in 5 episodes
• Clustering — 1× in this paper · explained in 2 episodes
• Empirical Coverage — 1× in this paper · explained in 2 episodes
• Foundation Model — 1× in this paper · explained in 3 episodes
• Longitudinal Data — 1× in this paper · explained in 2 episodes
• Principal Component Analysis (PCA) — 1× in this paper · explained in 4 episodes
• Verification — 1× in this paper · explained in 2 episodes

Sources

• Universal CT Representations from Anatomy to Disease Phenotype through Agglomerative Pretraining
• Anticipatory Digital Twins for Online Head-and-Neck Adaptive Proton Therapy via Foundation-Model Registration

Related papers

• Reduced NEXI protocol for the quantification of human gray matter microstructure on the Connectome 2.0 scanner
• Edge-Aligned Beam Placement in Scanning Probe Tomography via Reconstruction-Free Sequential Design of Experiments
• Validation of a Computational Respiratory System Model for Mechanical Ventilation