Democratizing Clinical Tumor Whole Genome Sequencing: 18-hour End-to-end Analysis via Trillion-parameter Large Language Models Locally Deployed on Consumer-grade Hardware

arXiv:2609.17620 · q-bio.GN, cs.LG · Submitted 2026-09-14 · Read on arXiv

q-bio.GN, cs.LG

Submitted: 2026-09-14

Updated: 2026-09-14

Comments: 11 pages. Corresponding author: Yili Xu(22465225@qq.com)

License: http://arxiv.org/licenses/nonexclusive-distrib/1.0/

Terminology

Accuracy — 21× in this paper · explained in 1 episode
Core — 11× in this paper · explained in 2 episodes
Adaptation — 7× in this paper · explained in 1 episode
F1 Score — 5× in this paper · explained in 3 episodes
Quantization — 4× in this paper · explained in 12 episodes
Edge AI — 3× in this paper · explained in 2 episodes
Generalization — 3× in this paper · explained in 13 episodes
Adaptive Heterogeneous Memory Scheduling — 2× in this paper · explained in 1 episode
Benchmark — 2× in this paper · explained in 2 episodes
Feature Extraction — 2× in this paper · explained in 2 episodes
Pruning — 2× in this paper · explained in 4 episodes
Alignment — 1× in this paper · explained in 1 episode
Cancer Genome Atlas — 1× in this paper
Distillation — 1× in this paper · explained in 2 episodes
Error Decomposition — 1× in this paper · explained in 3 episodes
Foundation Model — 1× in this paper · explained in 3 episodes
Knowledge Distillation — 1× in this paper · explained in 11 episodes
Large Language Models (LLMs) — 1× in this paper · explained in 6 episodes
Sparsity — 1× in this paper · explained in 4 episodes
Transformer — 1× in this paper · explained in 2 episodes