Deploying DeepSeek 175B Locally on a Single Consumer-Grade RTX 4060 Laptop with 32GB RAM for 200k-Scale Protein-Ligand Virtual Screening

arXiv:2608.30877 · cs.LG · Submitted 2026-08-31 · Read on arXiv

cs.LG

Submitted: 2026-08-31

Updated: 2026-08-31

License: http://arxiv.org/licenses/nonexclusive-distrib/1.0/

Terminology

• Accuracy — 15× in this paper · explained in 1 episode
• Adaptation — 6× in this paper · explained in 1 episode
• Core — 6× in this paper · explained in 2 episodes
• Generalization — 3× in this paper · explained in 13 episodes
• Quantization — 3× in this paper · explained in 12 episodes
• Edge AI — 2× in this paper · explained in 2 episodes
• Large Language Models (LLMs) — 2× in this paper · explained in 6 episodes
• Pruning — 2× in this paper · explained in 4 episodes
• Benchmark — 1× in this paper · explained in 2 episodes
• Distillation — 1× in this paper · explained in 2 episodes
• Domain Adaptation — 1× in this paper · explained in 5 episodes
• Error Decomposition — 1× in this paper · explained in 3 episodes
• Feature Extraction — 1× in this paper · explained in 2 episodes
• Knowledge Distillation — 1× in this paper · explained in 11 episodes

Sources

• DeepSeekMoE: Towards Ultimate Expert Specialization in Mixture-of-Experts Language Models

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