Smooth % MinMax: A Differentiable Relaxation for Codon Harmonization

arXiv:2607.03881 · q-bio.QM, cs.LG · Submitted 2026-07-04 · Read on arXiv

q-bio.QM, cs.LG

Submitted: 2026-07-04

Updated: 2026-08-26

Comments: 17 pages, 2 figures

Code: https://github.com/CISgroup/SmoothMinMax

License: http://arxiv.org/licenses/nonexclusive-distrib/1.0/

Terminology

• Adaptation — 6× in this paper · explained in 1 episode
• Codon Adaptation Index — 2× in this paper
• Fidelity — 2× in this paper · explained in 2 episodes
• Loss Function — 2× in this paper · explained in 2 episodes
• Abundance — 1× in this paper · explained in 1 episode
• Accuracy — 1× in this paper · explained in 1 episode
• Alignment — 1× in this paper · explained in 1 episode
• Attention Mechanism — 1× in this paper · explained in 3 episodes
• Cross-Attention Mechanism — 1× in this paper · explained in 2 episodes
• Embeddings — 1× in this paper · explained in 2 episodes
• Interpretability — 1× in this paper · explained in 15 episodes
• Multi-objective Optimization — 1× in this paper · explained in 4 episodes
• Objective Function — 1× in this paper · explained in 2 episodes

Sources

• mRNA Design and Optimization with Deep Knowledge-Infused Approach

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